Glioblastoma is the most common, malignant primary brain tumor with a median survival time of fifteen months. Single tumor cells escape surgical resection and become resistant to radiation and chemotherapy by spreading into microenvironments that support viability. Caleb is focusing on two specific proteins: CD44 (a cell-surface glycoprotein that directly links with the cell cytoskeleton) and Src kinase (involved in the upregulation of signaling pathways)both of which promote the tumors invasion. CD44 interacts with Src activity to control actin proteins that form microfilaments fundamental to cell shape, division, and motility. Caleb is determining whether CD44-mediated invasion (through direct linkage to the cytoskeleton) or Src kinase signaling is more fundamental to glioblastoma, an essential question toward deriving future therapies. Ex vivo experimentation will uncover the importance of this CD44-Src complex.
The recent economic recession and political turmoil in Brazil has driven over half of Brazil’s Haitian migrant population northbound towards the United States. This wave of over 50,000 Haitians has been met by tightening immigration policies from both the United States and Mexico, making the journey more difficult and dangerous and transforming Mexico into a country of destination. This flow of Haitian refugees is overwhelmingly male, despite the fact that women account for nearly half of the global migrant and refugee population. I hypothesize that gender and race are fundamental in understanding migration, as they determine different opportunities, risks and vulnerabilities faced in transit and upon arrival. This research seeks to understand how gender, race and class intersect and shape every stage of the migration process.
Current Bio: Grace is a full-time research assistant at Columbia University. Haas Scholars Project: Emotion regulation is the process by which individuals manage their emotions. A robust set of findings suggests that certain emotion regulation strategies promote well-being whereas others undermine well-being. This project will utilize romantic relationships as the social context in which to examine the effects of various emotion regulation strategies. Work related to this topic has either not considered partner perceptions or has relied on experimental paradigms that have low ecological validity. To address these limitations, Grace Allison will utilize surveys and observed relationship-specific conversations between couples to assess partner perceptions of emotion regulation and relationship quality. Enhanced understanding of adaptive and maladaptive strategies between romantic partners could have implications for life and relationship satisfaction, as well as therapy interventions. She will also compare effects across Western and Eastern cultural contexts.
In many materials, the application of an electric field leads to a separation of positive and negative charges, inducing a polarization in the material. In ferroelectrics, such a polarization exists in the material without the application of an external field. Analogously, the alignment of electron spins in ferromagnetic materials results in a magnetic polarization in the absence of an external magnetic field. Bismuth ferrite (BiFeO3) is a rare material in which both of these states exist at room temperature and are coupled: applying an external electric field can switch the magnetization and vice-versa. Using pulsed laser deposition, Dan will synthesize ultrathin films of BiFeO3 and aims to demonstrate reversible switching between the materials structural ground states; functionality that has the potential to be used in next-generation low-power memory storage devices.
Research suggests collective bargaining improves the unionized worker’s wages and working conditions, in addition to those of non-union status in the same field. Despite the organizing successes of San Francisco’s Lusty Lady, neither working conditions nor take home earnings for Bay Area strippers improved overall. How do these particular workers secure a better working environment and basic labor rights? This ethnographic study will utilize mixed-methods to analyze possibilities for collective action within this industry. Utilizing a comparative analysis of two cases labor organization, Raven will travel to New York to study current organization efforts and conduct an historical analysis of the successes of efforts at the Lusty Lady in San Francisco. This research intends to provide insight into the possibilities for collective organization within the ever-growing body of contract workers.
Current Bio: Jasmine is a first year MS/PhD at Berkeley in EECS. Haas Scholars Project: One focus of point-of-care devices is to improve accessibility of essential diagnostic tools by utilizing miniaturized, accurate and low-cost optical systems. Printed organic optoelectronics are one such technology that have the potential to improve the optical sensing schemes of these systems. Because organic optoelectronics are processed in solution, they can be easily scaled for large-area manufacturing and roll-to-roll processing, leading to low-production costs. Jasmine aims to design a point-of-care device utilizing printed optoelectronics for fluorescent biomarker sensing and demonstrate the efficacy of this system on procalcitonin, which has been shown to be a useful biomarker for managing antibacterial treatment. Her goal is to demonstrate the use of printed optoelectronics for point-of-care applications as a cheap alternative to current optical sensing systems
Elven anti-air Nike Missile Sites ringed San Francisco in a line of atomic protection, poised for launch at Soviet bombers that never came from 1950 to 1974. Only Nike Missile site SF-88 has been preserved in a coat of fresh paint that crowds of the curious have toured since 1974 in the Golden Gate National Recreation Area. Sebastian Herics will be tracing the cultural memory of the Cold War by comparing Nike missile sites, both preserved and left to ruin, through the eyes of the military, the city of San Francisco, and various social movements in the BayWhat does it mean to have Cold War memories both preserved and left to crumble? He will be flying to Washington D.C. for various military archives.
Ariadna’s research project will focus on the West Berkeley Shellmound, an ancient village site that was once situated on the San Francisco Bay shoreline in Berkeley, California. Her thesis is directed toward understanding how Native American societies interacted with their environment during the last 5000 years. Research will be conducted on animal remains from the shellmound, using curated materials excavated in the early and mid-twentieth century, to understand ancient fisheries and fishing practices. Archaeological analyses of fisheries can contribute to historical baseline data relevant for conservation biology, restoration ecology, and fisheries management. As historical survey of fishes occurred after impacts to the bay, archaeological data will provide a source of historical information to understand the structure, range, and relative abundance of ancient fishes that can inform contemporary fisheries management.
Lissa grew up in Chula Vista, California, where many are transfronterizos, students and workers who live in Mexico but commute to the U.S almost daily. Nancy Wonders advances the theory of border performativity where she argues borders are not only geographically constituted, but also socially constructed via the performance of various state actors in an elaborate dance with ordinary people who seek freedom of movement and identification. Thus, border performativity points to different technologies of control such as the social construction of the illegal and the securitisation of migration. Lissas research seeks to understand how transfronterizo students engage in border performativity. She will center how transfronterizos give meaning to their every day realities through in-depth interviews that focus on the interpretations and experiences of these students as border commuters.
Current Bio: Since graduation, Rebecca has been working in Research Administration for the UC system. Through this job, she has been able to assist many UC professors and researchers in securing grants and contacts funding for a variety of research projects. Haas Scholars Project: Rebecca grew up in a small town and watched the rural drug scourge destroy the young lives in her community. Now, she is using her Berkeley education to understand this phenomenon. This summer she will be traveling to rural Tuolumne County, California to do ethnographic fieldwork exploring how community attachment impacts rural youth opioid abuse. To explore this, she will be conducting a series of in-depth interviews; she will be interviewing recovering opioid addicts and public service officials. Her goal is to gain a deep understanding about why the young use drugsparticularly opioidsat such pervasive rates in small towns. She hopes to use this information for […]