Early ART or PrEP? A Comparative Analysis of Effectiveness and Cost of HIV Prevention through Antiretroviral Drugs

Worldwide, we have more than 33 million people living with HIV (human immunodeficiency virus). It remains a challenge to find the best prevention methods. Keng’s research compares two new biomedical prevention methods that have used ART (antiretroviral therapy) to prevent HIV transmission in discordant couples (one member is infected but the other is not). One method is PrEP (pre-exposure prophylaxis), where the uninfected person takes antiretroviral drugs, and the other method begins ART in the infected member earlier than is clinically recommended to prevent transmission. The clinical trials data from both methods are published and available for analysis. Keng will use meta-analysis and cost-effectiveness analysis to compare and contrast both prevention strategies for a cohort of heterosexual couples living in southern Africa.

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Evolution of the Rostrum in Stomatopod Crustaceans

Stomatopods, also known as mantis shrimp, are some of the coolest marine crustaceans. They are powerful predators (for their size, at least) and are concentrated in tropical waters all over the world. The stomatopod rostrum, a segment of exoskeleton near the eyes, ranges from a simple triangular shape to something that looks more like a crown or the curved top of a palace. This summer, Irene will be looking into the evolutionary motivations of stomatopod rostrum variation. She plans to determine the function of the rostrum and the reasons for its wide variation by compiling environmental data, taking high-speed videos of stomatopod behaviors, and comparing rostrum shapes to their phylogeny.

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